Abstract

P 099

Clinical implications of abnormal aspect of the optic nerve head in preterm children

Marta Pawlak, Anna Gotz- Wieckowska
Department of Ophthalmology, University of Medical Sciences, Poznan, Poland

Objective
To evaluate clinical implications of abnormal aspect of the optic nerve head in preterm children.
Methods
24 eyes of 12 patients, aged 7 to 15 with abnormal aspect of the optic nerve head, born before gestational age of 36 weeks were examined. Children treated for retinopathy of prematurity were excluded from the study. Following examinations were performed: visual acuity, colour vision, contrast sensitivity, visual field, VEP, axial length, refractive error. Optical coherence tomography (OCT) measurement of foveal thickness and retinal nerve fiber layer thickness (RNFL) was performed.
Results
The material comprised children born between 27 and 35 gestational age, with an Apgar score in 1st minute from 2 to 9. Best corrected visual acuity ranged for RE from 0.8 to 1.0, for LE from 0.9 to 1.0. Refraction error ranged for RE from -1.0 to +5.5, for LE from -1.0 to +5.75. Contrast sensitivity score, measured by means of Pelli-Robson chart, was for RE from 1.50 to 1.95, for LE from 1.35 to 1.95. The latency of P 100 in the visual evoked potentials ranged for RE from 96 to114 ms, for LE from 98 to 113 ms, while amplitude N75/P100 ranged for RE from 8.47 to 32.1 uV, for LE from 6.93 to 28 uV. Foveal thickness ranged for RE from 172 to 222 microns, for LE from 161 to 219 microns. Retinal nerve fiber layer thickness was for RE in upper quadrant 90 to 138 microns, in nasal quadrant 51 to 81 microns, in lower quadrant 91 to 145 microns, in temporal quadrant 31 to 74 microns  and for LE respectively: 98 to 142 microns, 59 to 110 microns, 84 to 164 microns, 31 to 73 microns. Axial length ranged for RE from 19.97 to 23.97 mm, for LE from 19,67 to 24.01 mm.
Conclusions
After preliminary analysis of the results, it seems that abnormal aspect of the optic nerve head in preterm children does not have much influence on visual function. Correlation with control group is planned.

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