Abstract

P 120

Standard Automated Perimetry (SITA 24-2 standard algorithm) versus matrix frequency doubling technology perimetry in patients with ocular hypertension and normal subjects

Julia Lamparter1, Andreas Schulze1, Shakhsanam Aliyeva1, Manfred Berres2, Norbert Pfeiffer1, Esther M. Hoffmann1
1Universitäts-Augenklinik Mainz; 2University of Applied Sciences Koblenz, RheinAhrCampus Remagen, Mainz

Objective
To evaluate the relationship and agreement between standard automated perimetry (SAP) and Matrix frequency doubling technology (FDT) in patients with ocular hypertension and healthy subjects.
Methods
Forty-five eyes of forty-five ocular hypertensives and thirty eyes of thirty healthy control subjects were included in this prospective study. All patients underwent complete ophthalmic examination, including slit-lamp biomicroscopy, intraocular pressure measurement, pachymetry, and dilated fundus examination, and showed reliable visual field tests. One randomly selected eye of each participant was examined with SAP (Swedish Interactive Threshold Algorithm [SITA] Standard 24-2 test) and Matrix-FDT (24-2 threshold test), in random order. Mean deviation, pattern standard deviation, each visual field test location, and specific sectors of the visual field were compared between both techniques and within groups.
Results
In both groups, mean deviation values of SAP and Matrix-FDT correlated significantly (r = 0.44 and 0.60, p-value < 0.005). Pattern standard deviation showed no significant correlation in healthy subjects but correlated significantly in patients (r = 0.47, p-value < 0.005). In the healthy subject group, a significant correlation between SAP and Matrix FDT was shown in the supero-temporal and infero-temporal sectors of the visual field (r = 0.46 and 0.37, p-value < 0.05). In patients, supero-temporal, supero-nasal and nasal sectors correlated significantly (r = 0.52, 0.61 and 0.35, p-values ≤ 0.02). The correlation pattern of individual visual field test locations appeared heterogenous in both groups.
Conclusions
SAP and Matrix-FDT correlate well in ocular hypertensive patients and healthy subjects. In ocular hypertensives the techniques showed good correlation in the supero-temporal, supero-nasal, and nasal sectors. Poor agreement was found in the temporal, infero-temporal and infero-nasal visual field sectors. Further investigations should elucidate whether the missing correlation might be related to early retinal fiber layer damage in these regions of the disc, recognized by one of the visual field instruments.

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