Abstract

FR.19.01

Characterization of intraocular lens surfaces with the “atomic force microscop”

Rupert Wolfgang Strauß1, Wolfgang Gsenger2, Kurt Schilcher2, Martin Dirisamer1, Johannes Burger1, Siegfried Priglinger1
1Augenklinik, AKH Linz, Linz, Österreich, 2Fachhochschule, Linz, Österreich

Objective
Characterization of intraocular lens surfaces with the “atomic force microscop”, eespecially appearance of different parameters and morphology of the surface.
Methods
A total of 14 different intraocular lenses of different companies (AC-60 (OIL®), AF-1 (Hoya®), Tecnis ZA9003 (AMO®), SN60AT (Alcon®), SN60WF (Alcon®), Acri Smart 36 A (Acri Tec®), Quatrix (Corneal®)) were analysed using the atomic force microscope by contact-mode und tapping-mode. This procedure was applied in intraocular lenses without further manipulation. In a second step, three different lenses were under sterile conditions used in an usual application procedure during a standard cataract operation, e.g. they were folded by an experienced cataract surgeon, loaded in a shooting system and pushed through the system.
Results
Using the “atomic force microscope” a characterization of surface properties could, especially the roughness, could be determined. Comparing untouched lenses and those which were undergone an application procedure, an increase of surface roughness between 26 % and 50 % could be observed in last ones. Furthermore, a scratch on the surface of an IOL was observed after the application procedure which may be derived from the procedure.
Conclusions
The „atomic force microscope“ offers new possibilities for characterization of intraocular lenses. The observed increase of surface roughness after the use in the application system may contribute to the development of posterior capsule opacification. Further studies are necessary to evaluate these findings.

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