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Abstract

FR.19.09

Determination of anterior chamber depth and iridocorneal angle for the risk assessment of phakic intraocular lens implantation

Florian Rüfer1, Anke Schröder1, Alexa Klettner1, Adjoa Frimpong-Boateng1, Carl Erb2
1Augenklinik, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Kiel; 2Abteilung für Augenheilkunde, Schlosspark-Klinik, Berlin

Objective
For the implantation of phakic intraocular lenses, a minimal anterior chamber depth of 3.0 mm is recommended in literature. Anterior chamber depth and iridocorneal angle are age dependent. Thus the aim was to quantify the impact of age, gender and refraction.
Methods
The anterior chamber depth and the iridocorneal angle in 8 positions were determined with the OrbscanII in 390 normal subjects aged 10 – 80 years. By means of multiple regression analysis, the influence of age, gender and spherical equivalent was quantified and tested for statistical significance. Using model calculations, the risk for the implantation of phakic intraocular lenses in myopia, hyperopia and astigmatism was assessed.
Results
The influence of age (p < 0.0001), spherical equivalent (p < 0.0001) and gender (p = 0.0036) on anterior chamber depth were significant (multiple regression equation: anterior chamber depth (mm) = 3.08 – 0.0115  * age (years) – 0.0562 * spherical equivalent (dpt) + 0.0996 * gender (m=1, f=2)). The influence of age (p = 0.0007), gender (p < 0.0001) and spherical equivalent (p = 0.001) on the mean iridocorneal angle were likewise significant (multiple regression equation: mean iridocorneal angle (°) = 32.97 – 0.865 * gender (m=1, f=2) – 0.017 * age (years) – 0.121 * spherical equivalent (dpt)). The narrowest iridocorneal angle was located nasal superiorly, the widest inferiorly. The strongest age related decrease of the iridocorneal angle was detected superiorly and nasally, the weakest temporally and inferiorly.
Conclusions

The anterior chamber depth is decreasing by about 0.58 mm in 50 years. During this period, the anterior chamber can drop below the critical depth of 3.0 mm after phakic intraocular lens implantation in myopics. Due to a less elevated anterior chamber, the risk is even higher in astigmatism and hyperopia. In the elderly, the asymmetry of the iridocorneal angle leads to limited space especially in the superior and nasal quadrants. Using the underlying data, the indication for phakic intraocular lens implantation should be reconsidered individually.
 
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