Abstract

FR.20.10

Selective retina therapy (SRT) for acute central serous retinopathy

Carsten Klatt1, Mark Saeger1, Till Oppermann1, Erk Poerksen2, Jost Hillenkamp1, Johann Roider1
1Augenklinik, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Kiel, 2Hamburg

Objective
To evaluate the efficacy of Selective Retina Therapy (SRT) as a treatment of acute central serous retinopathy (CSR).
Methods
Prospective randomized clinical trial including 30 patients with untreated acute CSR with a minimum history of 3 months. 14 patients were treated with SRT (pulsed double-Q-switched Nd-YLF laser, wavelength 527 nm, t=1.7 µs, energy 100–370 μJ). 16 untreated patients served as controls. Before SRT and 3 months after SRT best-corrected ETDRS-visual acuity (BCVA) was assessed. The maximal distance between the retinal pigment epithelium (RPE) and the outer retina in the area of subretinal fluid accumulation was measured by OCT. Leakage of subretinal fluid was assessed by fluorescein angiography (FA).
Results
3 months after SRT mean BCVA had increased by significantly more letters as compared to the control group: 11,8 (standard deviation, SD=6,9) vs. 6,3 (SD=8,9) (p=0,04). Mean maximal distance between the RPE and the outer retina in the area of subretinal fluid accumulation had decreased significantly more after SRT as compared to the control group: 140 μm (SD=179) vs. 41 μm (SD=148) (p=0,03). In 9 of 14 patients after SRT and in 6 of 15 patients in the control group no leakage was seen in FA at 3 months follow-up.
Conclusions
SRT appears to expedite both functional recovery and the re-absorption of subretinal fluid as compared to untreated controls. Adverse effects were not observed after SRT.

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