Abstract

FR.23.01

Subconjunctival biochip for photometric blood glucose measurement

Gerd U. Auffarth, Christoph Hasslacher, Angela Ehmer, Julia Mutzek, Annett Mannsfeld, Il-Joo Limberger, Tanja M. Rabsilber
International Vision Correction Research Centre (IVCRC), Augenklinik, Universität Heidelberg, Heidelberg

Objective
Experimental and clinical evaluation of a subconjunctival biochip for blood glucose measurements in diabetes mellitus patients.
Methods
In 16 eyes of 16 patients with a mean age of 50.0±14.6 years (range 22 to 65 years) a hydrogelic biochip was implanted subconjunctivaly. 11 patients had a diabetes mellitus type I and 5 patients type II. Postoperatively photometric measurements of the biochip were compared with laboratory blood glucose and standardized blood glucose measurement devices.
Results
All implantations and postoperative outcomes were uneventful. The photometric blood glucose values showed a very good correlation to both other measurement techniques in hypo as well as in hyperglycaemic status.
Conclusions
Photometric blood glucose measurements with the subconjunctival biochip showed a high patient compliance and a good correlation to current glucose measurements.

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